Litcius/Paper detail

Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells

Sjoukje J. C. van der Stegen, Pieter L. Lindenbergh, Roseanna M. Petrovic, Hongyao Xie, Mame P. Diop, Vera Alexeeva, Yuzhe Shi, Jorge Mansilla‐Soto, Mohamad Hamieh, Justin Eyquem, Annalisa Cabriolu, Xiuyan Wang, Ramzey Abujarour, Tom T. Lee, Raedun Clarke, Bahram Valamehr, Maria Themeli, Isabelle Rivière, Michel Sadelain

2022Nature Biomedical Engineering71 citationsDOIOpen Access PDF

Topics & Concepts

CD8Cytotoxic T cellT-cell receptorBiologyInduced pluripotent stem cellCell biologyImmunologyT cellChimeric antigen receptorAntigenIn vitroImmune systemEmbryonic stem cellGeneticsGeneCAR-T cell therapy researchCRISPR and Genetic EngineeringViral Infectious Diseases and Gene Expression in Insects