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Obesity negatively impacts maintenance of antibody response to COVID-19 vaccines

Camille Chauvin, Sruthi Vijaya Retnakumar, Jagadeesh Bayry

2023Cell Reports Medicine21 citationsDOIOpen Access PDF

Abstract

Severe obesity accelerates the decline of neutralizing antibodies to COVID-19 vaccines contributing to increased risk of hospitalization from breakthrough SARS-CoV-2 infections. 1 These findings have repercussion on the vaccination policy for SARS-CoV-2 variants and other infectious diseases like influenza in obese population.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)VaccinationObesityMedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakAntibody responsePopulationAntibodyVirologyImmunologyPandemicEnvironmental healthInfectious disease (medical specialty)Internal medicineOutbreakDiseaseSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesDiabetes and associated disorders
Obesity negatively impacts maintenance of antibody response to COVID-19 vaccines | Litcius