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Hydrogen sulfide promotes lateral root formation in peach through persulfidation of <scp>SnRK1α</scp> kinase

Xuelian Wu, Anqi Du, Jiahui Liang, Zhe Wang, Yuansong Xiao, Futian Peng

2025Plant Biotechnology Journal8 citationsDOIOpen Access PDF

Abstract

Summary Root development is crucial for the growth and yield of horticultural crops. Hydrogen sulfide (H 2 S), an important gasotransmitter, has been shown to regulate lateral root (LR) formation in plants, including peach ( Prunus persica ). However, its specific regulatory mechanism remains largely unclear. Here, we show that the energy/metabolic sensor SUCROSE NON‐FERMENTING RELATED KINASE 1 (SnRK1) mediates the control of peach LR growth by H 2 S. PpSnRK1 activity in peach roots is enhanced with H 2 S to promote LR generation. Cys419, Cys430 and Cys505 residues in the catalytic α‐subunit of PpSnRK1 are modified by H 2 S persulfidation. Reduced persulfidation inhibits the H 2 S‐induced PpSnRK1 activity. Mutating Cys419 and Cys430 of PpSnRK1α severely impedes H 2 S‐promoted LR formation. LATERAL ORGAN BOUNDARIES DOMAIN 16 (LBD16) is a transcription factor essential for LR initiation. Further evidence shows that PpSnRK1α interacts with PpLBD16 in the nucleus, thereby enhancing the transcription of LR development‐related genes PpCNGC1 ( CYCLIC NUCLEOTIDE‐GATED ION CHANNEL 1 ) and PpEXPB2 ( EXPANSIN‐B2 ). In peach roots, transcription of these two genes is markedly up‐regulated by H 2 S‐induced PpSnRK1 activity. Silencing of PpLBD16 , PpEXPB2 or PpCNGC1 significantly reduces exogenous H 2 S‐induced LR formation. In situ hybridization analysis shows that they are strongly expressed in peach LR primordia along with PpSnRK1α . Our data reveal an interaction between H 2 S signal and SnRK1 kinase, providing mechanistic insights into the shaping of agronomically important root systems.

Topics & Concepts

BiologyBimolecular fluorescence complementationTranscription factorCell biologyLateral rootPrimordiumProtein subunitGene silencingTranscription (linguistics)GeneArabidopsisBiochemistryMutantPhilosophyLinguisticsPlant Molecular Biology ResearchPlant nutrient uptake and metabolismPotato Plant Research
Hydrogen sulfide promotes lateral root formation in peach through persulfidation of <scp>SnRK1α</scp> kinase | Litcius