Discovery of Helminthosporin, an Anthraquinone Isolated from <i>Rumex abyssinicus</i> Jacq as a Dual Cholinesterase Inhibitor
Augustin Ntemafack, Vijay K. Nuthakki, Mohd Abdullaha, Qazi Parvaiz Hassan, Sumit G. Gandhi, Sandip B. Bharate
Abstract
cm/s). In a nutshell, helminthosporin has been identified as a brain permeable dual cholinesterase inhibitor, and thus its further synthetic exploration is warranted for optimization of its potency.
Topics & Concepts
AnthraquinoneCholinesteraseDual (grammatical number)RumexBotanyChemistryTraditional medicineBiologyArtMedicinePharmacologyLiteratureOrganic chemistryCholinesterase and Neurodegenerative DiseasesMedicinal Plants and NeuroprotectionPhytochemistry and biological activity of medicinal plants