Novel Action Targets of Natural Product Gliotoxin in Photosynthetic Apparatus
Yanjing Guo, Jing Cheng, Yuping Lu, He Wang, Yazhi Gao, Jiale Shi, Cancan Yin, Xiaoxiong Wang, Shiguo Chen, Reto J. Strasser, Sheng Qiang
Abstract
-site through two hydrogen bonds between GT and D1-Ser264 and D1-His252. A hydrogen bond is formed between the aromatic hydroxyl oxygen of GT and the residue Ser264 in the D1 protein. The 4-carbonyl group of GT provides another hydrogen bond to the residue D1-His252. So, it is concluded that GT is a novel natural PSII inhibitor. In the future, GT may have the potential for development into a bioherbicide or being utilized as a lead compound to design more new derivatives.
Topics & Concepts
PlastoquinoneChlamydomonas reinhardtiiPhotosystem IIThylakoidPhotosynthesisChlamydomonasChemistrySpinachPhotosystemBiologyBiophysicsPhotochemistryStereochemistryBiochemistryChloroplastMutantGenePhotosynthetic Processes and MechanismsPlant Stress Responses and ToleranceAlgal biology and biofuel production