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Upstream open reading frames mediate autophagy-related protein translation

Ying Yang, Damián Gatica, Xu Liu, Runliu Wu, Rui Kang, Daolin Tang, Daniel J. Klionsky

2022Autophagy10 citationsDOIOpen Access PDF

Abstract

5' UTR, 5' untranslated region; Atg, autophagy-related; CDS, coding sequence; Cvt, cytoplasm-to-vacuole targeting; HBSS, Hanks' balanced salt solution; PA, protein A; PE, phosphati-dylethanolamine; PIC, preinitiation complex; PtdIns3K, phosphatidylinositol 3-kinase; qRT-PCR, quantitative reverse transcription PCR; Ubl, ubiquitin-like; uORF, upstream open reading frame; WT, wild-type.

Topics & Concepts

BiologyAutophagyOpen reading frameTranslation (biology)Upstream open reading frameCell biologyReading (process)Upstream (networking)GeneticsMessenger RNAApoptosisPeptide sequenceGeneComputer sciencePolitical scienceLawComputer networkCRISPR and Genetic EngineeringRNA and protein synthesis mechanismsAutophagy in Disease and Therapy
Upstream open reading frames mediate autophagy-related protein translation | Litcius