Cullin-independent recognition of HHARI substrates by a dynamic RBR catalytic domain
Katherine H. Reiter, Alex Zelter, Maria K. Janowska, Michael Riffle, Nicholas Shulman, Brendan MacLean, Kaipo Tamura, Matthew Chambers, Michael J. MacCoss, Trisha N. Davis, Miklós Guttman, Peter S. Brzović, Rachel E. Klevit
Topics & Concepts
Ubiquitin ligaseUbiquitinUbiquitin-Protein LigasesSubstrate (aquarium)CullinChemistryStereochemistryRing (chemistry)BiophysicsCatalysisCell biologyBiochemistryBiologyEcologyOrganic chemistryGeneUbiquitin and proteasome pathwaysGlycosylation and Glycoproteins ResearchCancer-related Molecular Pathways