Lysosomal functions and dysfunctions: Molecular and cellular mechanisms underlying Gaucher disease and its association with Parkinson disease
Mia Horowitz, Hila Braunstein, Ari Zimran, Shoshana Revel‐Vilk, Özlem Göker-Alpan
Topics & Concepts
SynucleinopathiesGlucocerebrosidaseAlpha-synucleinBiologyParkinson's diseaseParkinsonismLewy bodyUnfolded protein responseDopaminergicTFEBLysosomal storage diseaseNPC1LysosomeNeurodegenerationCell biologyDiseaseNeuroscienceInternal medicineMedicineGeneticsDopamineBiochemistryGeneEnzymeEndoplasmic reticulumIntracellularEndosomeLysosomal Storage Disorders ResearchCellular transport and secretionCalcium signaling and nucleotide metabolism