Incidence and Clinical Features of Venous Thromboembolism in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) in Japan
Yugo Yamashita, Yuuki Maruyama, Hirono Satokawa, Yuji Nishimoto, Ichizo Tsujino, Hideki Sakashita, Hiroko Nakata, Yoshinori Okuno, Yoshito Ogihara, Sen Yachi, Naoki Toya, Masami Shingaki, Satoshi Ikeda, Naoto Yamamoto, Shizu Aikawa, Nobutaka Ikeda, Hiroya Hayashi, Shingo Ishiguro, Eriko Iwata, Michihisa Umetsu, Akane Kondo, Takehisa Iwai, Takao Kobayashi, Makoto Mo, Norikazu Yamada, on behalf of the Taskforce of VTE and COVID-19 in Japan Study
Abstract
BACKGROUND: Coronavirus disease 2019 (COVID-19) reportedly causes venous thromboembolism (VTE), but the status of this complication in Japan was unclear. METHODS AND RESULTS: , P=0.04), and a higher proportion had a severe status for COVID-19 compared with those without. There was no significant difference in the proportion of patients alive at discharge between patients with and without VTE (80.0% vs. 88.6%, P=0.48). Among 8 pulmonary embolism (PE) patients, all were low-risk PE. CONCLUSIONS: Among a relatively small number of patients undergoing contrast-enhanced CT examination in Japanese real-world clinical practice, there were no VTE patients among those with mild COVID-19, but the incidence of VTE seemed to be relatively high among severe COVID-19 patients, although all PE events were low-risk without significant effect on mortality risk.