Is the anti-aging effect of ACE2 due to its role in the renin-angiotensin system?—Findings from a comparison of the aging phenotypes of ACE2-deficient, Tsukuba hypertensive, and Mas-deficient mice—
Hikari Takeshita, Kōichi Yamamoto, Masaki Mogi, Satoko Nozato, Hiromi Rakugi
Topics & Concepts
Renin–angiotensin systemAngiotensin-converting enzyme 2EndocrinologyPhenotypeInternal medicineAngiotensin IIReceptorAngiotensin-converting enzymeEnzymeChemistryBiologyMedicineGeneBiochemistryBlood pressureCoronavirus disease 2019 (COVID-19)DiseaseInfectious disease (medical specialty)Renin-Angiotensin System StudiesHormonal Regulation and HypertensionApelin-related biomedical research