Litcius/Paper detail

Activation mechanism of PINK1

Zhong Yan Gan, Sylvie Callegari, Simon A. Cobbold, Thomas R. Cotton, Michael J. Mlodzianoski, Alexander F. Schubert, Niall D. Geoghegan, Kelly L. Rogers, Andrew Leis, Grant Dewson, Alisa Glukhova, David Komander

2021Nature202 citationsDOIOpen Access PDF

Topics & Concepts

PINK1MitophagyAutophosphorylationMitochondrionCell biologyPhosphorylationKinaseBiologyUbiquitinChemistryBiophysicsBiochemistryProtein kinase AAutophagyGeneApoptosisAutophagy in Disease and TherapyLysosomal Storage Disorders ResearchParkinson's Disease Mechanisms and Treatments