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Lysosome-targeting chimaeras for degradation of extracellular proteins

Steven M. Banik, Kayvon Pedram, Simon Wisnovsky, Green Ahn, Nicholas M. Riley, Carolyn R. Bertozzi

2020Nature1,103 citationsDOIOpen Access PDF

Topics & Concepts

LysosomeCell biologyExtracellularInternalizationEndosomeBiologyMembrane proteinProtein degradationChemistryBiochemistryIntracellularReceptorEnzymeMembraneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis
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