Pancreatic stellate cells derived exosomal miR-5703 promotes pancreatic cancer by downregulating CMTM4 and activating PI3K/Akt pathway
Mingzhe Li, Huahu Guo, Qi Wang, Kai Chen, Marko Kornmann, Xiaodong Tian, Yinmo Yang
Topics & Concepts
Pancreatic cancerPI3K/AKT/mTOR pathwayHepatic stellate cellProtein kinase BCancer researchChemistryMedicineCell biologySignal transductionBiologyCancerPathologyInternal medicineExtracellular vesicles in diseaseMicroRNA in disease regulationCancer Mechanisms and Therapy