Recent Advances in Copper-Catalyzed Radical C–H Bond Activation Using N–F Reagents
José María Muñoz‐Molina, Tomás R. Belderraín, Pedro J. Pérez
Abstract
This Short Review is aimed at giving an update in the area of copper-catalyzed C–H functionalization involving nitrogen-centered radicals generated from substrates containing N–F bonds. These processes include intermolecular Csp3–H bond functionalization, remote Csp3–H bond functionalization via intramolecular hydrogen atom transfer (HAT), and Csp2–H bond functionalization, which might be of potential use in industrial applications in the future. 1 Introduction 2 Intermolecular Csp3–H Functionalization 3 Remote Csp3–H Functionalization 4 Csp2–H Functionalization 5 Conclusion
Topics & Concepts
Surface modificationChemistryIntramolecular forceIntermolecular forceRadicalReagentPhotoredox catalysisHydrogen bondPhotochemistryCopperCombinatorial chemistryCatalysisOrganic chemistryMoleculePhotocatalysisPhysical chemistryCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSynthesis and Catalytic Reactions