The glucocorticoids prednisone and dexamethasone differentially modulate T cell function in response to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade
Isobel Okoye, Lai Xu, John Walker, Shokrollah Elahi
Topics & Concepts
CTLA-4Immune systemImmune checkpointPrednisoneT cellDexamethasoneImmunotherapyMedicineJurkat cellsPeripheral blood mononuclear cellImmunologyBlocking antibodyInternal medicineCancer researchEndocrinologyAntibodyBiologyIn vitroBiochemistryCancer Immunotherapy and BiomarkersCancer, Stress, Anesthesia, and Immune ResponseImmune Cell Function and Interaction