Mitochondrial versus microsomal bioactivation of paracetamol by human liver and kidney tissues
Ege Arzuk, Mehmet Tokdemır, Hi̇lmi̇ Orhan
Topics & Concepts
MicrosomeMitochondrionMitochondrial permeability transition poreMitochondrial toxicityCYP2E1KidneyChemistryCYP3A4Cell biologyPharmacologyBiochemistryBiologyCytochrome P450MetabolismEndocrinologyEnzymeApoptosisProgrammed cell deathDrug-Induced Hepatotoxicity and ProtectionLiver Disease and TransplantationDrug Transport and Resistance Mechanisms