Berberine and its structural analogs have differing effects on functional profiles of individual gut microbiomes
Leyuan Li, Chang Lu, Xu Zhang, Zhibin Ning, Janice Mayne, Yang Ye, Alain Stintzi, Jia Liu, Daniel Figeys
Abstract
microbiome assay can assess differential regulating effects of compounds with subtle differences and reveals that compound analogs can have distinct effects on the microbiome.
Topics & Concepts
BiologyMicrobiomeVerrucomicrobiaAkkermansiaFirmicutesButyrateProteobacteriaBacteroidetesBerberineHalomonasBiochemistryBacteroidesBacteriaGeneticsFermentationGene16S ribosomal RNABerberine and alkaloids researchGut microbiota and healthGinseng Biological Effects and Applications