Recent Advances on Fluorescent Sensors for Detection of Pathogenic Bacteria
Xu Tang, Qi Qi, Binrong Li, Zhi Zhu, Jian Lu, Lei Liu
Abstract
Pathogenic bacteria are one of the main causes of diseases and have become an important public health problem threatening human health and socio-economic development. Therefore, it is particularly important to develop an efficient and convenient detection method. Fluorescence detection has become a highly concerned analytical technology, which has gradually emerged in the aspect of pathogen detection, and is favored by researchers. In this review, we summarized a series of sensing strategies for pathogen detection based on fluorescence response signals in recent years, including single molecule fluorescent probes, biosensors, nanocomposite sensors and strategies for integrating different recognition elements with nanomaterials, along with the advantages and disadvantages of various design strategies. Based on the existing research reports, the existing problems and future research challenges of fluorescent sensor technology are proposed.