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A chiral MOF membrane for enantioselective amino acid separation

Jinhua Xu, Jinyu Zhang, Wenmin Zhang, Shiye Xie, Lan Zhang

2025Chemical Communications6 citationsDOI

Abstract

-tryptophan. The membrane exhibits exceptional enantioselectivity towards amino acids (ee value: 99.38%) through synergistic effects of hydrogen bonding and spatial hindrance. This strategy demonstrates the potential of amino acid-based chiral centers for high-performance separation membranes.

Topics & Concepts

Enantioselective synthesisSteric effectsHydrogen bondChemistryAmino acidMembraneTryptophanStereochemistryCombinatorial chemistryOrganic chemistryMoleculeCatalysisBiochemistryMetal-Organic Frameworks: Synthesis and ApplicationsMolecular Sensors and Ion DetectionAdvanced biosensing and bioanalysis techniques