A convergent multicomponent synthesis, spectral analysis, molecular modelling and docking studies of novel 2H-pyrido[1,2-a]pyrimidine-2,4(3H)-dione derivatives as potential anti-cervical cancer agents
Nishat Afza, Prince Trivedi, Abha Bishnoi, Shama Parveen, Saurabh Kumar, Monisha Banerjee
Topics & Concepts
ChemistryADMEHeLaPyrimidineStereochemistryLipophilicityDocking (animal)In silicoMolecular modelQuinolineQuantitative structure–activity relationshipCombinatorial chemistryIn vitroBiochemistryOrganic chemistryNursingGeneMedicineSynthesis and biological activityMulticomponent Synthesis of HeterocyclesSynthesis and Characterization of Heterocyclic Compounds