Novel paraben derivatives of tetracyclic spermine cyclotriphosphazenes: synthesis, characterization and biosensor based DNA interaction analysis
Perihan Kızılkaya, Elif Şenkuytu, Derya Davarcı, Uğur Pala, Zehra Ölçer, Gönül Yenilmez Çiftçi
Abstract
A new series of paraben-substituted dispiroansa (tetracyclic) spermine derivatives of cyclotriphosphazenes likely to be biologically active were synthesized for the first time and their effects on DNA were studied.
Topics & Concepts
ChemistrySpermineParabenCombinatorial chemistryDNAStereochemistryOrganic chemistryBiochemistryPreservativeEnzymePolyamine Metabolism and ApplicationsFlame retardant materials and propertiesPhenothiazines and Benzothiazines Synthesis and Activities