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Targeted protein degradation as a powerful research tool in basic biology and drug target discovery

Tao Wu, Hojong Yoon, Yuan Xiong, Sarah E. Dixon-Clarke, Radosław P. Nowak, Eric S. Fischer

2020Nature Structural & Molecular Biology187 citationsDOIOpen Access PDF

Topics & Concepts

Drug discoveryProtein functionComputational biologyBiologyProtein degradationFunction (biology)UbiquitinChemical biologyProtein–protein interactionBioinformaticsBiochemistryCell biologyGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysAutophagy in Disease and Therapy
Targeted protein degradation as a powerful research tool in basic biology and drug target discovery | Litcius