Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway
Zhanjun Ma, Jingjing Yang, Yang Yang, Xuexi Wang, Guohu Chen, An-Cheng Shi, Yubao Lu, Shouning Jia, Xuewen Kang, Ligong Lu
Topics & Concepts
PTENPI3K/AKT/mTOR pathwayProtein kinase BChemistryOsteosarcomaRosmarinic acidCancer researchSignal transductionPharmacologyCell biologyBiochemistryBiologyAntioxidantPlant-Derived Bioactive CompoundsNatural Products and Biological ResearchCancer, Lipids, and Metabolism