Cutaneous thrombosis associated with skin necrosis following Oxford‐AstraZeneca COVID‐19 vaccination
Ravi Ramessur, Nawar Saffar, Branislav Czako, Ashish Agarwal, K. Batta
Abstract
A 73-year-old male presented with left shin ulceration two weeks after receiving his first dose of the ChAdOx1 nCov-19 (Oxford-AstraZeneca) vaccine. He had a background of atrial fibrillation with ischemic cardiomyopathy and had been on several longstanding medication, including apixaban. Within 24 hours of vaccination, the patient became generally unwell with fever and headache. After resolution of these systemic symptoms, on the third day after vaccination, he developed left shin erythema and blistering which rapidly ulcerated (see figure 1). On examination, he had two superficial ulcers with a necrotic base and a violaceous edge on the lateral aspect of his left shin, measuring approximately 2cm x 3cm in size.