Biophysical and in silico investigations of the molecular association between a potent RNA polymerase inhibitor, thiolutin and human serum albumin
Md. Zahirul Kabır, Zineddine Benbekhti, Nor Farrah Wahidah Ridzwan, Rabiâa Merrouche, Noureddine Bouras, Saharuddin Bin Mohamad, Saad Tayyab
Topics & Concepts
Human serum albuminChemistryQuenching (fluorescence)Molecular dynamicsHydrogen bondHydrophobic effectBinding constantBiophysicsBinding siteCircular dichroismStereochemistryBiochemistryFluorescenceComputational chemistryMoleculeOrganic chemistryBiologyQuantum mechanicsPhysicsProtein Interaction Studies and Fluorescence AnalysisSurfactants and Colloidal SystemsDrug Transport and Resistance Mechanisms