The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway

Sarah Naguib, Chloe Lopez-Lee, Eileen Ruth S. Torres, Se-In Lee, Jingjie Zhu, Daphne Zhu, Pearly Ye, Kendra Norman, Mingrui Zhao, Man Ying Wong, Yohannes A. Ambaw, Rodrigo Muñoz-Castañeda, Wei Wang, Tark Patel, Maitreyee Bhagwat, Rada Norinsky, Sue‐Ann Mok, Tobias C. Walther, Robert V. Farese, Wenjie Luo, Subhash C. Sinha, Zhuhao Wu, Li Fan, Shiaoching Gong, Li Gan