Protein Interactomes of Streptococcus mutans YidC1 and YidC2 Membrane Protein Insertases Suggest SRP Pathway-Independent- and -Dependent Functions, Respectively
Patricia Lara Vasquez, Surabhi Mishra, Senthil K. Kuppuswamy, Paula J. Crowley, L. Jeannine Brady
Abstract
Streptococcus mutans is a prevalent oral pathogen and major causative agent of tooth decay. Many proteins that enable this bacterium to thrive in its environmental niche and cause disease are embedded in its cytoplasmic membrane.
Topics & Concepts
Signal recognition particleTransloconMembrane proteinBiologyChaperone (clinical)Streptococcus mutansBlotProtein–protein interactionEscherichia coliTransport proteinBiochemistryCell biologyChemistryBacteriaSignal peptideMembranePeptide sequenceGeneticsGeneMedicinePathologyStreptococcal Infections and TreatmentsInfective Endocarditis Diagnosis and ManagementOral microbiology and periodontitis research