Mechanics and microstructure of blood plasma clots in shear driven rupture
Ranjini K. Ramanujam, Konstantinos Garyfallogiannis, Rustem I. Litvinov, J.L. Bassani, John W. Weisel, Prashant K. Purohit, Valerie Tutwiler
Abstract
the critical energy release rate, is relatively independent of the type of loading and is therefore a fundamental property of the gel. Ultrastructural studies and finite element simulations demonstrate that cracks propagate perpendicular to the direction of maximum stretch at the crack tip. These observations indicate that locally, the mechanism of rupture is predominantly tensile. Knowledge gained from this study will aid in the development of methods for prediction/prevention of thrombotic embolization.
Topics & Concepts
Shear (geology)MicrostructurePlasmaMechanicsMaterials sciencePhysicsComposite materialNuclear physicsBlood properties and coagulationTrauma, Hemostasis, Coagulopathy, ResuscitationHemoglobin structure and function