Effect of Polyphenols in Sea Buckthorn Berry on Chemical Mediator Release from Mast Cells
Shuxian Qiu, Anuu Zorig, Naoko Sato, Ai Yanagihara, T Kanazawa, Mikako Takasugi, Hirofumi Arai
Abstract
influx. These results indicate that isorhamnetin is the primary substance responsible for the antiallergic activity in SBB. In conclusion, SBB may alleviate Type-I allergy by inhibiting the release of chemical mediators from mast cells, and polyphenols may contribute to this effect.
Topics & Concepts
HistamineIsorhamnetinMyricetinChemistryMast cellPolyphenolDegranulationBiochemistryLeukotriene C4Biological activityPharmacologyAntioxidantLeukotrieneQuercetinBiologyImmunologyReceptorIn vitroKaempferolAsthmaPhytochemical and Pharmacological StudiesMedicinal plant effects and applicationsBotanical Studies and Applications