AQP3 Promotes the Invasion and Metastasis in Cervical Cancer by Regulating NOX4-derived H<sub>2</sub>O<sub>2</sub> Activation of Syk/PI3K/Akt Signaling Axis
Qixin Wang, Bingjie Lin, Hong-Jian Wei, Xin Wang, Xiaojing Nie, Yonghua Shi
Abstract
transport to contribute to the progression of cervical cancer, and AQP3 may be a potential target for the clinical treatment of advanced cervical cancer.
Topics & Concepts
NOX4Aquaporin 3Cancer researchProtein kinase BPI3K/AKT/mTOR pathwayChemistryGene knockdownNicotinamide adenine dinucleotide phosphateCell biologyNADPH oxidaseSignal transductionBiologyApoptosisOxidase testBiochemistryReactive oxygen speciesAquaporinEnzymeGenomics, phytochemicals, and oxidative stressGlutathione Transferases and PolymorphismsIL-33, ST2, and ILC Pathways