Genetic encoding of an esophageal motor circuit
Tatiana C. Coverdell, Ruei‐Jen Abraham‐Fan, Chen Wu, Stephen B.G. Abbott, John N. Campbell
Abstract
neurons has no effect on heart rate, a key parasympathetic function of the nAmb, whereas activating all of the nAmb neurons robustly suppresses heart rate. Together, these results reveal a genetically defined circuit for motor control of the esophagus.
Topics & Concepts
Nucleus ambiguusEsophagusOptogeneticsMotor neuronEfferentBiologyNeuroscienceCholinergicNeuronVagus nerveStimulationAnatomyCentral nervous systemMedulla oblongataAfferentSpinal cordNeuroscience of respiration and sleepAsthma and respiratory diseasesTracheal and airway disorders