High-salt diet mediates interplay between NK cells and gut microbiota to induce potent tumor immunity
Zaigham Abbas Rizvi, Rajdeep Dalal, Srikanth Sadhu, Yashwant Kumar, Shakti Kumar, Sonu Gupta, Manas Ranjan Tripathy, Deepak Kumar Rathore, Amit Awasthi
Abstract
activated NK cells, which inhibited tumor growth. These results indicate that HSD modulates gut microbiome that induces NK cell–dependent tumor immunity with a potential translational perspective.
Topics & Concepts
ImmunityBifidobacteriumBiologyGut floraImmunologyImmune systemEffectorNatural killer cellCancer researchCytotoxic T cellBacteriaLactobacillusBiochemistryIn vitroGeneticsGut microbiota and healthDiet and metabolism studiesTryptophan and brain disorders