Copper-catalyzed asymmetric dearomative alkynylation of isoquinolines
Xun Kou, Qingyang Zhao, Zheng‐Hui Guan
Abstract
Cu/(Ph-pybox)-catalyzed asymmetric dearomative alkynylation of isoquinolines has been developed, with high yields and enantioselectivities.
Topics & Concepts
AlkynylationChemistryCatalysisCopperEnantioselective synthesisIsoquinolineCombinatorial chemistryOrganic chemistryCatalytic C–H Functionalization MethodsSynthesis and Biological ActivityAsymmetric Synthesis and Catalysis