Characterization of a patient-derived variant of GPX4 for precision therapy
Hengrui Liu, F. Forouhar, Tobias Seibt, Russell P. Saneto, Kristen Wigby, Jennifer Friedman, Xin Xia, Mikhail S. Shchepinov, Sanath Kumar Ramesh, Marcus Conrad, Brent R. Stockwell
Topics & Concepts
GPX4Phospholipid-hydroperoxide glutathione peroxidasePoint mutationContext (archaeology)Missense mutationMutationEnzymeBiochemistryGeneBiologyChemistryGeneticsCell biologyGlutathioneGlutathione peroxidasePaleontologySelenium in Biological SystemsTrace Elements in HealthGlutathione Transferases and Polymorphisms