Brown adipose tissue-derived exosomes mitigate the metabolic syndrome in high fat diet mice
Xueying Zhou, Zhelong Li, Meihao Qi, Ping Zhao, Yunyou Duan, Guodong Yang, Lijun Yuan
Abstract
Collectively, our study showed that BAT-Exos significantly mitigated the metabolic syndrome in HFD mice. Detailed elucidation of the reactive molecules and mechanism of action would provide new insights in combating obesity and related disorders.
Topics & Concepts
MicrovesiclesBrown adipose tissueAdipose tissueBioenergeticsMetabolic syndromeInternal medicineEndocrinologyBiologyWhite adipose tissueObesityMitochondrionOil Red OMedicineCell biologyBiochemistryAdipogenesismicroRNAGeneAdipose Tissue and MetabolismCardiovascular Disease and AdiposityExtracellular vesicles in disease