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Modulated Gut Microbiota for Potential COVID-19 Prevention and Treatment

Shuai Zhao, Pengya Feng, Wenbo Meng, Weilin Jin, Xun� Li, Xiangkai Li

2022Frontiers in Medicine20 citationsDOIOpen Access PDF

Abstract

angiotensin-converting enzyme 2 receptors, which is highly expressed both in lung tissues and intestinal epithelial cells. The existence of the gut-lung axis in disease could be profoundly important for both disease etiology and treatment. Furthermore, several studies reported that infected patients suffer from gastrointestinal symptoms. The gut microbiota has a noteworthy effect on the intestinal barrier and affects many aspects of human health, including immunity, metabolism, and the prevention of several diseases. This review highlights the function of the gut microbiota in the host's immune response, providing a novel potential strategy through the use of probiotics, gut microbiota metabolites, and dietary products to enhance the gut microbiota as a target for COVID-19 prevention and treatment.

Topics & Concepts

Gut floraImmune systemImmunologyImmunityCoronavirusLungDiseaseBiologyGut–brain axisAngiotensin-converting enzyme 2Coronavirus disease 2019 (COVID-19)MedicineMicrobiologyInfectious disease (medical specialty)Internal medicineGut microbiota and healthDietary Effects on HealthCannabis and Cannabinoid Research
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