Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors: A preliminary attempt to unravel the enigma of glioblastoma
Kunal Nepali, Tsung‐I Hsu, Chien‐Ming Hsieh, Wei-Lun Lo, Mei-Jung Lai, Kai‐Cheng Hsu, Tony Eight Lin, Jian‐Ying Chuang, Jing‐Ping Liou
Topics & Concepts
ChemistryMemantineHDAC6In vivoHydroxamic acidPharmacologyApoptosisCell cycle checkpointCancer researchGlioblastomaGliomaCell cycleBiochemistryHistone deacetylaseReceptorStereochemistryMedicineBiologyHistoneBiotechnologyGeneNMDA receptorHistone Deacetylase Inhibitors ResearchGlioma Diagnosis and TreatmentPeptidase Inhibition and Analysis