Recent Advances in Synthesis of Chiral Thioethers
Hongyi Chen, Wenlong Jiang, Qingle Zeng
Abstract
Abstract Chiral thioethers is an important class of organosulfur molecules with extensive applications, especially in the field of medicine and organic synthesis. This review discusses the recent progress of synthesis of enantioenriched chiral thioethers and hopes to be helpful for related research in the future. It is summarized from organosulfur compounds‐participating organic reaction types, including nucleophilic substitution, cross coupling, sulfa‐Michael addition, sulfenylation, asymmetric allylic reaction, asymmetric Doyle‐Kirmse reaction, Pummerer‐type rearrangement, Smiles rearrangement, [2,3] Stevens and Sommelet‐Hauser rearrangement.
Topics & Concepts
Organosulfur compoundsSmiles rearrangementAllylic rearrangementEnantioselective synthesisOrganic synthesisChemistryNucleophilic substitutionOrganic moleculesOrganic chemistryCombinatorial chemistryMoleculeCatalysisSulfurSulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsSynthesis and Catalytic Reactions