Honokiol: A polyphenol neolignan ameliorates pulmonary fibrosis by inhibiting TGF-β/Smad signaling, matrix proteins and IL-6/CD44/STAT3 axis both in vitro and in vivo
Gauthami Pulivendala, Swarna Bale, Chandraiah Godugu
Topics & Concepts
In vivoPulmonary fibrosisSMADCD44FibrosisCancer researchHonokiolExtracellular matrixEpithelial–mesenchymal transitionMedicineIdiopathic pulmonary fibrosisTransforming growth factorImmunologyChemistryIn vitroPathologyLungBiologyPharmacologyCell biologyInternal medicineDownregulation and upregulationBiochemistryGeneBiotechnologyMagnolia and Illicium researchSpinal Hematomas and ComplicationsInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis