PEG shedding-rate-dependent blood clearance of PEGylated lipid nanoparticles in mice: Faster PEG shedding attenuates anti-PEG IgM production
Takuya Suzuki, Yuta Suzuki, Taro Hihara, Kenji Kubara, Keita Kondo, Kenji Hyodo, Kazuto Yamazaki, Tatsuhiro Ishida, Hiroshi Ishihara
Topics & Concepts
PEG ratioPEGylationChemistryPolyethylene glycolGene silencingSmall interfering RNAInternalizationRNA interferenceBiophysicsRNABiochemistryCell biologyBiologyCellGeneFinanceEconomicsRNA Interference and Gene DeliveryImmunotherapy and Immune ResponsesAdvanced biosensing and bioanalysis techniques