Modeling human multi-lineage heart field development with pluripotent stem cells
Donghe Yang, Juliana Gomez-Garcia, Shunsuke Funakoshi, Thinh Ngoc Tran, Ian Fernandes, Gary D. Bader, Michael A. Laflamme, Gordon Keller
Topics & Concepts
BiologyMesodermInduced pluripotent stem cellHeart developmentGastrulationLineage (genetic)Embryonic stem cellTranscriptomeMyocyteComputational biologyCell biologyGeneticsAnatomyBioinformaticsGeneGene expressionCongenital heart defects researchPluripotent Stem Cells ResearchSingle-cell and spatial transcriptomics