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Potential interventions for novel coronavirus in China: A systematic review

Lei Zhang, Yunhui Liu

2020Journal of Medical Virology1,387 citationsDOIOpen Access PDF

Abstract

An outbreak of a novel coronavirus (COVID-19 or 2019-CoV) infection has posed significant threats to international health and the economy. In the absence of treatment for this virus, there is an urgent need to find alternative methods to control the spread of disease. Here, we have conducted an online search for all treatment options related to coronavirus infections as well as some RNA-virus infection and we have found that general treatments, coronavirus-specific treatments, and antiviral treatments should be useful in fighting COVID-19. We suggest that the nutritional status of each infected patient should be evaluated before the administration of general treatments and the current children's RNA-virus vaccines including influenza vaccine should be immunized for uninfected people and health care workers. In addition, convalescent plasma should be given to COVID-19 patients if it is available. In conclusion, we suggest that all the potential interventions be implemented to control the emerging COVID-19 if the infection is uncontrollable.

Topics & Concepts

CoronavirusOutbreakVirologyCoronavirus disease 2019 (COVID-19)Psychological interventionMedicineVirusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Infection controlIntensive care medicineDiseaseImmunologyInfectious disease (medical specialty)Internal medicineNursingSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19