Saikosaponin D exhibits anti-leukemic activity by targeting FTO/m<sup>6</sup>A signaling
Kaiju Sun, Yangyang Du, Yuzhu Hou, Mingyue Zhao, Jiajia Li, Yazhe Du, Lingxiao Zhang, Changbao Chen, Hongmei Yang, Fei Yan, Rui Su
Abstract
A RNA methylation mediated the anti-leukemic actions of SsD, thereby opening a window to develop SsD as an epitranscriptome-base drug for leukemia therapy.
Topics & Concepts
Myeloid leukemiaCancer researchMyeloidMessenger RNAChemistryPharmacologyMedicineBiochemistryGeneRNA modifications and cancerRNA Research and SplicingGalectins and Cancer Biology