Biodegradable mPEG-<i>b</i>-poly(MDO-<i>co</i>-vinyl esters) block copolymers as a viable nanocarrier platform with tuneable disassembly
Arunpandian Balaji, Amber Prior, Rachel K. O’Reilly, Andrew P. Dove, Kristofer J. Thurecht, Craig A. Bell
Abstract
Xanthate-based copolymerisations of MDO and vinyl acetate-derivative monomers using a mPEG macroCTA created degradable amphiphilic block copolymers capable of self-assembly and crosslinking, where type of crosslinking influenced particle disassembly.
Topics & Concepts
CopolymerXanthateNanocarriersVinyl acetateMonomerAmphiphilePolymer chemistryMaterials scienceChemistryNanoparticleOrganic chemistryNanotechnologyPolymerAdvanced Polymer Synthesis and Characterizationbiodegradable polymer synthesis and propertiesSilicone and Siloxane Chemistry