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Scans per day as predictors of optimal glycemic control in people with type 1 diabetes mellitus using flash glucose monitoring: what number of scans per day should raise a red flag?

Fernando Sebastián‐Valles, Julia Martínez‐Alfonso, José Alfonso Arranz Martín, Jessica Jiménez‐Díaz, Iñigo Hernando Alday, Víctor Navas-Moreno, Teresa Armenta Joya, Maria del Mar Fandiño García, Gisela Liz Román Gómez, Luis Eduardo Lander Lobariñas, Purificación Martínez de Icaya, Miguel Sampedro‐Núñez, Vicente Martínez-Vizacaíno, Mónica Marazuela

2023Acta Diabetologica16 citationsDOIOpen Access PDF

Abstract

AIMS: This study aimed to determine the minimum frequency of flash glucose monitoring (FGM) scans necessary for optimal glycemic control in patients with type 1 diabetes (T1D). METHODS: Data were collected from 692 patients (47.5% female, with a median age of 47.4 years) who used FGM systems daily and recorded their clinical variables and device data. RESULTS: Logistic regression models showed that performing more than 12 scans per day was associated with improved T1D control (OR = 4.22, p < 0.001) and a reduction in HbA1c (7.6 vs 7.0%, 60-53 mmol/mol p < 0.001). However, those performing less than 6 scans showed no improvement in HbA1c (7.9 vs 7.8%, 63-61 mmol/mol p = 0.514). Thirteen daily scans were determined as the optimal cutoff point for predicting optimal glycemic control using a maximally selected rank algorithm. Significant reductions were observed in mean glucose (< 0.001), coefficient of variation (< 0.001), HbA1c (< 0.001), and an increase in TIR (< 0.001) in patients who performed more than 12 daily scans. CONCLUSIONS: The results suggest that a higher frequency of daily scans by T1D patients using FGM systems leads to improved chronic glycemic control. The minimum recommended frequency for optimal control is 13 scans per day, and more than 6 daily scans are needed to improve HbA1c.

Topics & Concepts

GlycemicMedicineDiabetes mellitusLogistic regressionInternal medicineCutoffType 1 diabetesCoefficient of variationNuclear medicineEndocrinologyMathematicsStatisticsPhysicsQuantum mechanicsDiabetes Management and ResearchHyperglycemia and glycemic control in critically ill and hospitalized patientsDiabetes Management and Education