Evaluation of affinity sensor response kinetics towards dimeric ligands linked with spacers of different rigidity: Immobilized recombinant granulocyte colony-stimulating factor based synthetic receptor binding with genetically engineered dimeric analyte derivatives
Ieva Plikusienė, Zigmas Balevičius, Almira Ramanavičienė, J. Talbot, Gitana Mickiene, Saulius Balevičius, Arūnas Stirkė, Alla Tereshchenko, Linas Tamošaitis, Gintautas Žvirblis, Arūnas Ramanavičius
Topics & Concepts
ChemistryReceptor–ligand kineticsKineticsLinkerBiophysicsProtein engineeringLigand (biochemistry)ReceptorPlasma protein bindingRecombinant DNABiochemistryBiologyEnzymeGeneQuantum mechanicsPhysicsComputer scienceOperating systemMonoclonal and Polyclonal Antibodies ResearchAdvanced biosensing and bioanalysis techniquesGlycosylation and Glycoproteins Research