Endoplasmic Reticulum Stress and Oxidative Stress in Inflammatory Diseases
Yun Tang, Xiangping Zhou, Ting Cao, En Chen, Yumeng Li, Wenbo Lei, Yibao Hu, Bisha He, Shuangquan Liu
Abstract
Endoplasmic reticulum (ER) stress and oxidative stress (OS) are often related states in cells as part of normal physiology but more frequently manifested in the pathophysiology of many diseases, particularly diseases involving acute or chronic inflammation. In this study, we reviewed recent findings about the role of ER stress and OS in the pathogenesis of inflammatory diseases.
Topics & Concepts
Endoplasmic reticulumOxidative stressUnfolded protein responseBiologyInflammationPathogenesisPathophysiologyImmunologyCell biologyEndocrinologyEndoplasmic Reticulum Stress and DiseaseHeme Oxygenase-1 and Carbon MonoxideInflammasome and immune disorders