Cooperative C–H activation of pyridine by PBP complexes of Rh and Ir can lead to bridging 2-pyridyls with different connectivity to the B–M unit
Yihan Cao, Wei‐Chun Shih, Nattamai Bhuvanesh, Jia Zhou, Oleg V. Ozerov
Abstract
The thermodynamic preference between two isomeric products of C–H activation of pyridine, with 2-pyridyl bridging boron and iridium or rhodium, primarily depends on the M–C bond strength.
Topics & Concepts
Bridging (networking)PyridineChemistryUnit (ring theory)Lead (geology)StereochemistryComputer scienceComputer networkMedicinal chemistryPsychologyGeologyPaleontologyMathematics educationCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsCyclopropane Reaction Mechanisms