NMDA receptors elicit flux-independent intracellular Ca2+ signals via metabotropic glutamate receptors and flux-dependent nitric oxide release in human brain microvascular endothelial cells
Sharon Negri, Pawan Faris, Claudia Maniezzi, Giorgia Pellavio, Paolo Spaiardi, Laura Botta, Umberto Laforenza, Gerardo Biella, Francesco Moccia
Topics & Concepts
Cell biologyMetabotropic glutamate receptorNMDA receptorGlutamate receptorMetabotropic glutamate receptor 1Metabotropic receptorNeuroscienceBiologyIonotropic glutamate receptorChemistryIonotropic effectReceptorBiochemistryNeuroscience and Neuropharmacology ResearchPhotoreceptor and optogenetics researchNeuroinflammation and Neurodegeneration Mechanisms