Mechanistic investigation of 1,3-dipolar cycloaddition between bifunctional 2-pyridylselenyl reagents and nitriles including reactions with cyanamides
Alexey A. Artemjev, Alexey S. Kubasov, Maxim L. Kuznetsov, Mariya V. Grudova, Victor N. Khrustalev, Andreii S. Kritchenkov, Alexander G. Tskhovrebov
Abstract
2-Pyridylselenyl reagents react with cyanamides to furnish pyridine-fused selenodiazolium salts. Theoretical calculations suggested that the coupling of 2-pyridylchalcogenyl halides and nitriles is an asynchronous cycloaddition reaction.
Topics & Concepts
CycloadditionBifunctionalReagentPyridineChemistryHalideCombinatorial chemistry1,3-Dipolar cycloadditionOrganic chemistryComputational chemistryCatalysisOrganic Chemistry Cycloaddition ReactionsOrganoselenium and organotellurium chemistrySulfur-Based Synthesis Techniques